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Abelson murine leukemia virus

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  1. (Ab-MLV, A-MuLV) is a retrovirus (Class VI) used to induce transformation of murine lymphoid cells

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 11, 2009
  2. As a retrovirus, it has a single-stranded, positive sense RNA genome which replicates via a DNA intermediate mediated by a reverse transcriptase

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 11, 2009
  3. named for the American pediatrician Herbert T. Abelson who first described and isolated it

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 11, 2009
  4. A-MuLV causes a rapidly progressive lymphosarcoma known as Abelson disease in mice, which is a type of leukemia that does not involve the thymus

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 11, 2009
  5. However, this is only possible when the host cell is co-infected with a helper virus which provides functions it needs to be able to replicate which is does not code for in its own genome such as a reverse transcriptase and some major structural prot

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 11, 2009
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