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Meleda disease

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  1. also called Mljet disease, keratosis palmoplantaris and transgradiens of siemens, is an extremely rare autosomal recessive congenital skin disorder in which dry, thick patches of skin develop on the soles of the hands and feet, a condition known as p

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 20, 2009
  2. most common on the Dalmatian island of Mljet (or Meleda), thought to be because of a founder effect

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 20, 2009
  3. of autosomal recessive inheritance

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 20, 2009
  4. may be caused by a mutation on the SLURP1 gene, located on chromosome 8

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 20, 2009
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