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Cholesterol 7 alpha-hydroxylase
also called 7 alpha-hydroxylase and has one more synonym

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  1. the rate-limiting enzyme in the synthesis of bile acid from cholesterol, catalyzing the formation of 7-alpha-hydroxycholesterol

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 28, 2009
  2. downregulated by Sterol regulatory element binding proteins (SREBP) when plasma cholesterol levels are low

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 28, 2009
  3. upregulated by the nuclear receptor LXR (liver X receptor) when cholesterol (specifically - oxysterol) levels are high

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 28, 2009
  4. The effect of this upregulation is to increase the production of bile acids and reduce the level of cholesterol in hepatocytes

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 28, 2009
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