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Complement factor I

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  1. (fI) is a protein of the Complement system, first isolated in 1966 in guinea pig serum that regulates complement activation by cleaving cell-bound or fluid phase C3b and C4b

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 2, 2009
  2. Both heavy and light chains bear Asn-linked glycans, on three distinct glycosylation sites each

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 2, 2009
  3. deficiency in turn leads to low levels of complement component 3 (C3) in plasma, due to unregulated activation of the complement alternative pathway, and it has been associated with recurrent bacterial infections in children

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 2, 2009
  4. The gene for Factor I in humans is located on chromosome 4 Factor I is synthesised mostly in the liver, and is initially secreted as a single 88 kDalton gene product

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 2, 2009
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