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Androgen insensitivity syndrome

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  1. Although many distinct mutations have been discovered, the clinical manifestations have been divided into six phenotypes, which roughly correspond to increasing amounts of androgen effect due to increasing tissue responsiveness

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 11, 2009
  2. also referred to as androgen resistance syndrome, is a set of disorders of sexual differentiation caused by mutations of the gene encoding the androgen receptor

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 11, 2009
  3. The nature of the resulting problem varies according to the structure and sensitivity of the abnormal receptor

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 11, 2009
  4. Most forms of AIS involve variable degrees of undervirilization and/or infertility in XY persons of either gender

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 11, 2009
  5. A person with complete androgen insensitivity syndrome (CAIS) has a female external appearance despite a 46XY karyotype and undescended testes, a condition termed "testicular feminization" in the past

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on February 11, 2009
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