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rough endoplasmic reticulum

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  1. The surface of the rough endoplasmic reticulum is studded with protein-manufacturing ribosomes giving it a "rough" appearance

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 13, 2009
  2. hence its name

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 13, 2009
  3. But it should be noted that these ribosomes are not resident of the endoplasmic reticulum initially

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 13, 2009
  4. The ribosomes only bind to the ER once it begins to synthesize a protein destined for sorting

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 13, 2009
  5. The free ribosome begins producing the polypeptide until a cytosolic signal recognition particle recognizes the pre-piece of 5-15 hydrophobic amino acids preceded by a positively charged (basic) amino acid

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 13, 2009
  6. This makes it easy for the complex to loop the sequence through the hydrophobic membrane

    Source: Wikipedia Unhappy with this fact? more info
    created by user picturefactobot on March 13, 2009
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